Biohub open-sources AI world model for protein biology and drug design
Biohub released ESMC, ESMFold2, and ESM Atlas, an open AI ecosystem for protein structure prediction and therapeutic design. ESMFold2 designs novel binders against cancer and immunology targets with lab-validated affinity and specificity, compressing years of screening into days. The entire toolkit is freely available to researchers worldwide.
AI
More AI →Biohub open-sources AI world model for protein biology and drug design
Biohub releases open AI models that map the protein universe and design lab-validated therapeutic binders in days instead of years.
Google to pay SpaceX $920M monthly for xAI data center GPU capacity
Google will pay SpaceX $920 million a month for 32 months to rent roughly 110,000 GPUs inside xAI data centers, giving Google Cloud bridge capacity for Gemini Enterprise as SpaceX prepares its record IPO.
OpenAI Ships Million-Line Product Written Entirely by Codex Agents
OpenAI details building and shipping a full product with zero manually-written code using Codex agents, achieving roughly 10x speed and redefining engineering as steering rather than coding.
Microsoft Discovery Goes GA on Azure, Powering Majorana 2 Quantum Chip with Agentic AI
Microsoft Discovery’s agentic AI platform hits GA on Azure, directly enabling the Majorana 2 quantum chip’s 1,000× reliability leap and a 2029 quantum computer target.
Anthropic embeds engineers in NSA to deploy Mythos for offensive cyber operations
Anthropic embedded engineers in the NSA to deploy its unreleased Mythos AI for offensive cyber operations, even as it sues the Pentagon over military AI restrictions.
U.S. in talks to take OpenAI stake via public wealth fund
The White House and Sam Altman are in talks over a potential U.S. government stake in OpenAI, possibly via donated equity to seed a public wealth fund.
DevOps
More DevOps →GitHub scrubs 70+ Microsoft repos as Miasma worm breaks CI/CD pipelines
GitHub disabled 70+ Microsoft repos in under two minutes after the Miasma worm infected projects via compromised commits, breaking CI/CD pipelines and triggering RCE in developer tools.
Microsoft Launches Logic Apps Automation SaaS with Built-In AI Agents and RAG
Microsoft unveils Azure Logic Apps Automation, a managed SaaS for building production-grade AI automations without integration developers, featuring built-in RAG, agent support, and zero infrastructure assembly.
Microsoft Launches Azure Logic Apps Automation with Built-in AI Agents and Zero-Infra RAG
Microsoft unveils Azure Logic Apps Automation, a managed SaaS for building production-grade AI automations with built-in security, Knowledge as a Service, and natural language interfaces.
Netflix automates dynamic repartitioning to fix Cassandra wide partitions at scale
Netflix details how it automatically repartitions petabyte-scale time series data in Cassandra to tame wide partitions, cut tail latency, and eliminate timeouts without manual intervention.
PostgreSQL 19 Beta 1 Debuts with Async I/O Scaling, SQL/PGQ, and Parallel Vacuum
PostgreSQL 19 Beta 1 is now available, previewing async I/O scaling, parallel autovacuum, SQL/PGQ graph queries, SNI-based TLS, and faster foreign-key inserts.
Pinterest Deduplicates URLs at Scale Using Content Fingerprints
Pinterest's MIQPS system uses content fingerprints to intelligently strip noisy query parameters from URLs, slashing duplicate-content processing costs across millions of domains at scale.
MedTech
Biohub open-sources AI world model for protein biology and drug design
Biohub releases open AI models that map the protein universe and design lab-validated therapeutic binders in days instead of years.
NHS to issue half a million Copilot licenses to ease paperwork burden
NHS England is rolling out Microsoft Copilot to 505,000 staff after a pilot claimed the AI saved 43 minutes of admin daily, plus Copilot Studio for custom agents.
Open Source
More Open Source →Python JIT compiler faces removal from main branch over PEP process dispute
Python's steering council halts JIT compiler development on the main branch, threatening removal in six months unless a new PEP is submitted and approved to replace the current informational one.
PostgreSQL 19 Beta 1 Debuts with Async I/O Scaling, SQL/PGQ, and Parallel Vacuum
PostgreSQL 19 Beta 1 is now available, previewing async I/O scaling, parallel autovacuum, SQL/PGQ graph queries, SNI-based TLS, and faster foreign-key inserts.
Statistical Analysis Debunks Claims That Claude Increased Bugs in Rsync
A statistical analysis of 36 rsync releases finds no evidence that Claude-assisted commits increased bugs, debunking viral claims that sparked maintainer harassment.
Valve Acknowledges Steam P2P Latency Issues Affecting Israel and Middle East
Valve acknowledges Steam P2P networking issues forcing Israeli and Middle East players through high-latency SDR relays, making games unplayable despite 'Share IP' settings.
Microsoft Open-Sources pg_durable, a PostgreSQL Extension for Durable Functions
Microsoft open-sources pg_durable, a PostgreSQL extension that brings durable functions and stateful workflow orchestration directly into the database via background workers.
Alibaba Open-Sources LLM-Powered Code Review Tool with Agent Support
Alibaba open-sources Open Code Review, an LLM-powered CLI and GitHub Action for automated code reviews with Claude Code and agent integration.
Programming
More Programming →OpenAI Ships Million-Line Product Written Entirely by Codex Agents
OpenAI details building and shipping a full product with zero manually-written code using Codex agents, achieving roughly 10x speed and redefining engineering as steering rather than coding.
Inside Linear's Speed: Engineering a Local-First, Zero-Spinner UI
Linear achieves sub-100ms interactions by treating the browser as its primary database, using optimistic updates, and hiding every network request from users. Here's how to apply the same techniques.
Study Reveals Code Review Devours 60% of Tokens in AI-Driven Software Development
Study finds AI agent code review consumes 59% of tokens in software engineering workflows, revealing hidden costs lie in refinement rather than generation.
Python JIT compiler faces removal from main branch over PEP process dispute
Python's steering council halts JIT compiler development on the main branch, threatening removal in six months unless a new PEP is submitted and approved to replace the current informational one.
The $1,000 Secret Behind Your $100 AI Coding Subscription
An in-depth experiment with Claude Code reveals that heavy AI-assisted programming consumes tokens worth over $1,000 monthly at API rates, suggesting current consumer AI subscriptions are heavily subsidized and economically unsustainable for serious use.
Cursor updates Design Mode for visual, voice-driven AI agent editing
Cursor's updated Design Mode lets you point, draw, or narrate UI changes directly on your running app so AI agents can edit code in real time without breaking flow.
Security
More Security →GitHub scrubs 70+ Microsoft repos as Miasma worm breaks CI/CD pipelines
GitHub disabled 70+ Microsoft repos in under two minutes after the Miasma worm infected projects via compromised commits, breaking CI/CD pipelines and triggering RCE in developer tools.
Anthropic embeds engineers in NSA to deploy Mythos for offensive cyber operations
Anthropic embedded engineers in the NSA to deploy its unreleased Mythos AI for offensive cyber operations, even as it sues the Pentagon over military AI restrictions.
Ubiquiti Patches Critical UniFi OS Flaws Enabling Unauthenticated Root RCE
Ubiquiti patched three critical UniFi OS flaws that chain into unauthenticated root RCE with CVSS 10.0 scores, requiring immediate patching and full credential rotation.
Meta pushes for contempt ruling against NSO Group over fresh WhatsApp phishing
Meta is seeking contempt charges against Israeli spyware vendor NSO Group for allegedly targeting WhatsApp users with phishing campaigns, defying a permanent court injunction.
OpenAI introduces Lockdown Mode to block data exfiltration from prompt injection attacks
OpenAI rolls out Lockdown Mode, a strict security setting that disables live web browsing, agents, and external connections to block data exfiltration from prompt injection attacks.
Apple Publishes Formal Verification Blueprint for Quantum-Secure corecrypto
Apple published formal verification proofs and tools for its quantum-secure corecrypto implementations of ML-KEM and ML-DSA, aiming to guarantee mathematical correctness across billions of devices.
Tech
More Tech →Google to pay SpaceX $920M monthly for xAI data center GPU capacity
Google will pay SpaceX $920 million a month for 32 months to rent roughly 110,000 GPUs inside xAI data centers, giving Google Cloud bridge capacity for Gemini Enterprise as SpaceX prepares its record IPO.
Microsoft Discovery Goes GA on Azure, Powering Majorana 2 Quantum Chip with Agentic AI
Microsoft Discovery’s agentic AI platform hits GA on Azure, directly enabling the Majorana 2 quantum chip’s 1,000× reliability leap and a 2029 quantum computer target.
Microsoft Discovery AI Platform Goes GA on Azure, Accelerating Quantum Chip Breakthrough
Microsoft's Discovery AI agent platform hits GA on Azure, while its agentic AI helped design the Majorana 2 quantum chip, cutting the path to scalable quantum computers to 2029.
Google Signs $920M/Month SpaceX AI Compute Deal for 110K GPUs
Google agreed to pay SpaceX $920M monthly for access to 110,000 NVIDIA GPUs from October 2026 through June 2029, with strict delivery deadlines and opt-out clauses tied to Gemini Enterprise demand.
Google to Pay SpaceX Nearly $1 Billion Monthly in Cloud Deal
Google will pay SpaceX almost $1 billion monthly for cloud computing services, marking a massive infrastructure partnership between the tech and space giants.
Small modular nuclear reactor reaches criticality in first U.S. test
Antares' small modular reactor reached criticality at Idaho National Lab, becoming the first new U.S. design to achieve self-sustaining nuclear reactions.